My research focuses on environmental epidemiology, examining how environmental stressors—including air pollution, climate factors, and occupational exposures—affect health across the life course. I place particular emphasis on vulnerable populations, such as children, older adults, and pregnant women. By integrating advanced statistical methods with large-scale health databases and molecular biomarkers, I investigate both short- and long-term health effects and underlying biological mechanisms. My work adopts a multidisciplinary, life-course perspective to understand how environmental exposures influence metabolic and cardiometabolic health during critical developmental and aging windows. I further incorporate heterogeneous data analytics and real-time monitoring technologies to improve exposure assessment and identify early physiological responses. Through collaboration with the Multi-Country Multi-City Collaborative Research Network, I contribute Taiwan-based data to global climate and health research. Ultimately, my goal is to develop predictive indicators and mechanistic evidence that inform risk assessment, early prevention, and policy responses under a changing climate.
Huang CC, Pan SC, Chen PC, Guo YL (2025, Jul). Taiwan population-based epigenetic clocks and their application to long-term air pollution exposure. Environ Res, 277:121542
Pan SC, Chin WS, Huang CC, Chen YC, Wu CD, Hsu CY, Lin P, Chen PC, Guo YL (2025, Jan). Proximity to petrochemical industry and risk of childhood asthma occurrence. Int J Hyg Environ Health, 264:114515.
Chen SJ, Pan SC, Wu CD, Li H, Guo YL, Lin CH (2024, Dec). Long-term exposure to multiple air pollutants and risk of Parkinson's disease: a population based multipollutant model study. J Neurol Neurosurg Psychiatry, 334825.
